LSCI 106: ONLINE RESEARCH 1: INTRODUCTION TO ONLINE RESEARCH

Student Project Model

WEBLIOGRAPHY

by C. A.

RESEARCH QUESTION: What role do genes have in the development of alcoholism?

Introduction

Matt McGue started his longitudinal Twin Studies in the 1990’s and they indicated that genetics factors exerted a substantial influence on alcoholism risk in males but not females.  His recent work has shown that the age at which an individual first tries alcohol is predictive of a wide range of adult behavioral problems, including alcoholism, drug abuse, academic underachievement, and antisocial personality disorder. He also showed so far that the age at first drink is familial and, at least in males, heritable. Based on his findings he is hypothesizing that an early age at first drink is an indicator of vulnerability to disinhibitory behavior and psychopathology and he is continuing to explore in the Minnesota Twin Family study. (McGue)


GENERAL SEARCH WORKSHEET

CONCEPT #
Search Terms

 

1
Alcoholism
Alcoholi*
Alcoholi?
.
.
2
Genetics
Genes
Gene*
.
.
3
+alcoholic+genetic
.
.

.

.

 

 

SUBJECT HEADINGS

Ebsco Host:

OPIOIDS -- Physiological effect

DRINKING of alcoholic beverages

GENETIC code

MENTAL illness -- Genetic aspects

EVOKED potentials (Electrophysiology);

DUAL diagnosis; MENTAL illness

           

PLS Online Catalog:

Alcoholism -- Genetic aspects

Brain -- Effect of drugs on

Alcohol -- Physiological effect

Alcoholism -- Treatment

Alcohol, Ethyl -- adverse effects

Alcohol, Ethyl -- pharmacology

Alcoholism -- genetics.

Brain -- drug effects.

 Proquest Newspapers Database

Genetics

Alcoholism

Biomedical Research

Research Society on Alcoholism

 

WEBLIOGRAPHY

Blum, Kenneth. Alcohol and the Addictive Brain: New Hope for Alcoholics from Biogenetic Research. New York: Free Press, 1991.

“Gene Study Probes Link of Alcoholism to Depression.” Alcohol and Drug Abuse Weekly. 7 May 2001:1. Health Source: Nursing/Academic Edition. Ebsco Host. 5 May 2002. http://search.epnet.com/direct.asp?AN=4431933&db=hch&

Gianoulakis, Christina. “Influence of the endogenous opioid system on high “Influence of the endogenous opioid system on high alcohol consumption and genetic predisposition to alcoholism.” Journal of Psychiatry and Neuroscience, Sep.2001:304+. Nursing/Academic Edition. Ebsco Host. 1 May 2002. <http://search.epnet.com/direct.asp?AN=5290395&db=hch&>

Jang, Kerry L. et al. “Intra- and extra-familiar influences on alcohol and drug misuse: a Twin study of Gene-Environment Correlation.”  Addiction. Sept. 2001:1307. Academic Search Elite. Ebsco Host. 5 May. 2002.http://search.epnet.com/direct.asp?AN=5393112&db=afh&"

Madden, Pamela A. F. et al. “Smoking and the Genetic Contribution to Alcohol-Dependence Risk.” Alcohol Research & Health  2000:209+. MasterFILE Premier. Ebsco Host. 2 May 2002. <http://search.epnet.com/direct.asp?AN=4844204&db=f5h&>

McGue, Matt. “A Behavioral-Genetic Perspective on Children of Alcoholics.” Alcohol Health and Research World. 1997:210+. Academic Search Elite. Ebsco Host. 5 May 2002. http://search.epnet.com/direct.asp?AN=1136497&db=afh&

Matt McGue is a  Professor at the University of Minnesota. He teaches:             
1  Behavioral Genetics
2 Readings in Individual Differences and Behavioral Genetics 
3 Statistics for the Behavioral Sciences
He is a behavioral geneticist with two primary areas of research. The first concerns the development of substance disorders from adolescence to adulthood. Twin studies that he completed in the early 1990’s indicated that genetic factors exerted a substantial influence on alcohol risk in males but not females. So in 1990, he started the Minnesota Twin Family Study, a longitudinal investigation of 1400 families, each consisting of a pair of like sex adolescent twins and their parents.

National Council on Alcoholism and Drug Dependence. 14 March 2002. National Council on Alcoholism and Drug Dependence, Inc. 8 May 2002. http://www.ncadd.org/.

 

National Institute on Alcohol Abuse and Alcoholism.  May 2002, National Institutes of Health. 2 May 2002. http://www.niaaa.nih.gov/

The NIAAA supports and conducts biomedical and behavioral research on the

            causes consequences, treatment, and prevention of alcoholism and alcohol-related problems. They also provide leadership in the national effort to reduce the severe and often fatal consequences of these problems. They disseminate their research findings to health care providers, researchers, policymakers and the public.

 

Slutske, Wendy S. et al. “Personality and the Genetic Risk for Alcohol   Dependence.” Journal of Abnormal Psychology. Feb. 2002:124. Academic Search Elite. Ebsco Host. 5 May 2002. http://search.epnet.com/direct.asp?AN=6377326&db=afh&

Wendy Slutske is a Professor at the University of Missouri. Her education includes:

B.S. in Psychology, University of Wisconsin, Madison 1986

Internship in Clinical Pschology, Indiana School of Medicine 1991-92

Ph.D in Clinical Psychology, University of Minnesota 1993

NIMH Postdoctoral Fellow in Psychiatric Epidemiology and Biostatistics 1993-96

Wendy Slutske’s  research focuses primarily on the etiology and classification of externalizing psychopathology. She uses mainly behavioral genetic and epidemiologic methods to examine genetic and environmental risk and protective factors for externalizing psychopathology. The research is funded by grants from the National Institute on Alcohol Abuse and Alcoholism and the National Institute of Mental Health.

Her home page was last updated on July 14, 2001. Her work has been published in many professional journals such as The Journal of Consulting and Clinical Psychology and the Archives of General Psychiatry.

The Journal of Abnormal Psychology is a scholarly journal; it is published four times a year and is peer reviewed. It is published by the American Psychological Association in Washington, D. C. and was first published in August, 1990. They include articles on basic research and theory in the broad field of abnormal behavior. Each article represents an addition to knowledge and understanding of abnormal behavior either in etiology, description or change.

Weiss, Rick. “Discovery May be Brewing in Search for Genetic Link to Alcoholism” The Washington Post. 1 July 1996. Proquest Newspapers Database. 3 May 2002. http://proquest.umi.com/pqdlink?Ver=1&Exp=06-02-2002&VAULT=1&FMT=FT&DID=000000021819719&REQ=1&Cert=UPRtsupLXJpuaJIYuNwONTgGcutcpaaJNddbt402mIv0ee4ey%2bgjl2GoHNoF60WeJ%2fzDQd%2fuJJjtBqI4i%2fMLPw--

Rick Weiss is a science and medical reporter for the Washington Post. He came to the Post’s Health section in 1993 and moved to the national desk in January 1996, where he covers genetics, molecular biology and other topics in the life sciences. Weiss is 51 years old and he earned a B.S. in biology from Cornell University in 1974. For ten years, he worked as a licensed medical technologist in hospital laboratories, specializing in microbiology, serology and blood banking. In 1983 he entered the Graduate School of Journalism at the University of California, Berkeley, where he earned a Masters in Journalism. He has also worked for Health magazine and Science News magazine and Memorial Sloan-Kettering Cancer Center. This particular article would be valuable for historic material related to the Collaborative Study on Genetics, which was started in 1989 by the NIAAA, a division of the National Institutes of Health. http://www.santafe.edu/~johnson/sciwrite.weiss.html.

 The Washington Post newspaper is an operation division of the Washington Post Company. The Company is a diversified media company whose principal operations include newspaper and magazine publishing, television broadcasting, cable television services, test preparation and educational and career services. Company headquarters are in Washington, D.C.


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last revised: 5-7-02 by Eric Brenner, Skyline College, San Bruno, CA

These materials may be used for educational purposes if you inform and credit the author and cite the source as: LSCI 106 Online Research. All commercial rights are reserved. Send comments or suggestions to: Eric Brenner at brenner@smccd.net