Energy & Enzymes

Activation energy

Active site

Allosteric inhibition

Allosteric site

Apoenzyme

ATP

Catalyst

Competitive inhibition

Denaturation

Energy

Entropy (DS)

Enzyme

Enzyme-substrate complex

Feedback inhibition

Free energy (DG)

High-energy bond

Holoenzyme

Kilocalorie

Noncompetitive inhibition

Product

Saturation

Substrate

Turnover number

Oxidoreductases (1.)

Transferases (2.)

Hydrolases (3.)

Lyases (4.)

Isomerases (5.)

Ligases (6.)

Answers to study questions on the handout:

1a. Can't tell.

1b. DG' = 1.8 + 592 ln0.01 = 0.991

1c. -3.0 = 1.8 + 592ln[X]; [X] = 0.99

2. Phosphocreatine phosphate + ADP -> Creatine + ATP

DG°' = -10.3 kcal/mol + 7.3 kcal/mol = -3.0 kcal.mol