Topic 12 Sensory Mechanisms

Objectives

1.       Know the sensory Systems: Describe the three component parts of a typical sensory system

2.       Know three types of Sensory Receptors: Chemoreceptors Photoreceptors, thermoreceptors  and Nociceptors.

3.       Know how the Sensory Pathways functions: All sensory receptors convert stimulus energy to local, graded potentials, which may result in an action potential if the stimulus is intense or repeated fast enough

4.       Describe how muscle sense works.

5.       Somatic Sensations: Somatic sensations start in the receptor endings of surface tissues, skeletal muscles, and walls of internal organs: they then travel up the spinal cord to the somatosensory cortex of the brain to be interpreted

6.       Describe how hearing works by using mechanoreceptors

 

Important figures: Table 12.1, Fig 12.3 muscle and tendon receptors, 12.5 taste receptors, 12.6 smell receptors. 12.9 the structure of the human ear, fig 12.13 the structure of the eye, fig 12.16 structure of the retina.

1.       The actual structures that respond to our environment are called receptors.  Different types of receptors exist

  1. Many hundreds of different receptors exist for smell

1)       Each receptor can latch on to an odor molecules of a specific size and shape.

2)       The genes for receptor proteins belong to a large family of smell genes.

3)       Your sense of smell is a combination of inputs from dozens of receptors.

B.       Conversely, human taste buds can distinguish only four tastes.

  1. Color perception relies on just three photoreceptors for red, green and blue.

2.       Sensory Systems sometimes we get a better understanding of how humans work by trying to make artificial intelligence.  To see a discussion of androids click this link.

  1. Each sensory system has three component parts for a sensation to take place.

1)       Sensory receptors are the branched endings of sensory neurons or specialized cells adjacent to them that detect specific stimuli.

a)       Receptors are associated with specialized organs.

b)       A stimulus is a form of energy capable of eliciting a response by means of an action potential.

2)       Nerve pathways lead to the brain.

3)       Brain regions process the information into a sensation .

B.       Types of Sensory Receptors, mostly we sense change.

1)       Chemoreceptors detect ions or molecules: they include olfactory and taste receptors.

2)       Mechanoreceptors detect changes in pressure, position, or acceleration: they include receptors for touch, stretch, hearing, and equilibrium.

3)       Photoreceptors detect the energy of visible and ultraviolet light.

4)       Thermoreceptors detect radiant energy, including infrared.

5)       Nociceptors (pain receptors) detect tissue damage.

6)       Osmoreceptors detect changes in water volume (solute concentration) in surrounding fluid.

C.       Sensory Pathways

1)       All sensory receptors convert stimulus energy to local, graded potentials, which may result in an action potential if the stimulus is intense or repeated fast enough.

2)       Action potentials reach the brain via synapses with interneurons and provide the following information:

a)       Genetically determined networks of neurons in the brain can interpret incoming action potentials only in specific ways: for example receptors from eyes see only light.

b)       The stronger the stimulation of a receptor, the greater the frequency of action potentials.

c)       Strong stimulation causes a greater number of neurons to fire.

3)       Sensory adaptation is the reduction in frequency of depolarization due to a stimulus being maintained as a constant strength.

3.     Somatic Sensations

A.      Somatic sensations start in the receptor endings of surface tissues, skeletal muscles, and walls of internal organs: they then travel up the spinal cord to the somatosensory cortex of the brain to be interpreted.  Most pain receptors are near the surface of the body.

B.       Touch and Pressure

1)       These sensations are dependent on mechanoreceptors, which are dendrites of sensory neurons, with or without a capsule of epithelial or connective tissue.

2)       Many receptors sensitive to touch produce action potentials only when the stimulus begins and ends.

3)       Receptors sensitive to pressure respond to a constant stimulus.

C.      Temperature

1)       When the body surface temperature remains constant, the neuron messages to the brain are a steady stream.

2)       Increases in temperature cause an increase in firing.

3)       The mechanism for detection of cold has not been identified yet.

D.      Pain

1)       Pain is the perception of injury to some region of the body.

2)       Nociceptors in nearly all the body tissues pick up the signals.

a)       The messages are directed through the thalamus and on to the parietal lobe of the brain for interpretation.

b)       Responses are made to strong mechanical stimulation, intense heat and cold and chemical irritation.

3)       Much visceral pain is referred, that is felt as some distance from the real stimulation point.

E.       Muscle Sense

1)       Mechanoreceptors in skeletal muscle, joints, tendons, ligaments, and skin are responsible for awareness of the body’s position and of its limb movements.

2)       Stretch receptors in the muscle tissue respond in accordance with the degree and speed of muscle stretching.

4.        Taste and Smell

  1. Gustation: The sense of Taste

1)       Taste receptors in humans are part of the sensory organs called taste buds.

a)       Receptors are located on the tongue, roof of the mouth, throat and palate.

b)       The four general taste categories are sweet, sour, bitter and salty.

2)       The flavors of most foods are a combination of the four basic tastes plus sensory input form olfactory receptors in the nose.

       B. Olfaction: the sense of smell

1)       Olfactory receptors detect odors.

a)       Many times the receptors respond to molecules from food or predators (you can often smell muggers).

b)       The interpretation of smell is done by the olfactory bulbs located in the brain

2)       Olfaction is one of the most ancient senses, useful in survival.  Smells can also elicit very strong emotions.

3)        Humans also have a vomeronasal organ whose receptors can detect pheromones, which are signaling molecules with roles in sexual attraction.

 

5.       Hearing

A.      Hearing requires acoustical receptors that can detect vibrations, wavelike forms of mechanical energy that show amplitude (loudness)_ and frequency (pitch).

B.       The Ear

1)       The outer ear collects sound waves and channels them through a canal to an eardrum.

2)       Three small bones in the middle ear vibrate and amplify the sound.

3)       In the inner ear, pressure waves in the fluid of the cochlea, stimulate hair cells.

C.       Mechanism of hearing.

1)       Vibrations are passed form the tympanic membrane to the middle ear bones (malleus, incus, stapes) to the oval window stretched across the entrance to the cochlea

a)       Fluid in the cochlea responds to vibrations causing the basal membrane and hair cells in the organ of Corti, as well as those in the tectorial membrane, to bend sending action potentials via the auditory nerve to the brain.

b)       Loudness is determined by the total number of cells that become stimulated: tone or Pitch depends on the frequency of vibration.

2)       The round window at the far end of the cochlea serves as a release valve for the pressure waves.

3)       The Eustachian tube extending form the middle ear to the permit equalization of pressure.

 

6.        Balance

A.      The sense of balance depends on the organs of equilibrium.

1)       The vestibular apparatus is a closed system of fluid filled sacs and canals inside the ear.

a.        In the semicircular canals, whose canals are arranged in three planes of space, the jelly like cupula is distorted by movement resulting in the bending of hairs.

b.       Two fluid filled sacs (utricle and saccule) contain the otolith organs (hair cells) and otoliths (ear stones) that detect changes in orientation as well as acceleration and deceleration.

2)       Action potentials from different parts of the vestibular apparatus travel to reflex centers in the brainstem and the brain, to be interpreted for ordering compensatory movements necessary to maintain postural balance.

B.       Overstimulation of the hair cells of the vestibular apparatus can result in motion sickness.

7.        Overview of eye Structure and function

A.      Vision requires structures that are able to focus (lenses) light onto photoreceptors and brain centers that can interpret the patterns of action potentials received.

B.       Eye Structure

1)       Eyes are photoreceptor organs that contribute to image formation.

2)       The eye has three layers, sometime called “tunics”.

a.        The outer sclera (white of the eye) covers most of the eye: the cornea covers the front.

b.       The middle layer consists of a dark pigmented choroid, and iris that can enlarge or diminish the size of the pupil opening, and a lens whose shape can be altered by the ciliary body muscle.

c.        A clear aqueous humor bathes both sides of the lens and a vitreous humor fills the chamber behind the lens.

d.       The inner layer is the retina, whose axons converge to form the optic nerve.

C.       Focusing mechanisms

1)       Because of the bending of the light rays by the cornea, accommodation must be made by the lens so that the image is in focus on the retina.

2)       The ciliary muscle changes the shape of the lens to focus.

3)       If the lens cannot make sufficient adjustments of the eyeball is not shaped correctly, corrective lenses must be worn.

8.     From Neural Signaling to visual Perception

A.      Organization of the retina

1)       Photoreceptors, linked to neurons, are located in the retina.

a.        Rods are sensitive to dim light and detect changes in light intensity.

b.       Cones respond to high intensity light, contribute to sharp daytime vision, and are packed at the fovea: three types respond to red, green or blue light.

2)       The sense of vision is the result of processing the information through levels of synapsing neurons.

1)       Stimulation begins in the rods and cones, then moves to bipolar cells and ganglion cells, the axons of which form the optic nerves.

2)       Before leaving the retina, signals are dampened or enhanced by horizontal cells and amacrine cells.

B.       Neuronal responses to light

1)       Each rod contains molecules of rhodopsin that can be altered (cis retinal to trans retinal) by light, resulting in voltage changes in membranes.

2)       Cone cells do not use rhodopsin but have different visual pigments for each of the primary colors.

3)       Visual perception begins when light strikes receptive fields of ganglionic cells, each of which is responsible for a tiny circle on the retina.

4)       Axons of the optic nerves end in lateral geniculate nucleus, from which they proceed to the brains visual cortex, which has several visual fields sensitive to direction, movement, color and so on: her is where final interpretation of the signals is made to produce an organized sense of sight.

 

Questions to Think about

1 Why is it that the tastiest food is bland and flat when a person has a bad head cold?

2. What is motion sickness? 

3. How can it be controlled?

4.  Can you compare the function of vision as it occurs in a human to that of a computer?

7.         Many people become hard of hearing when they get older.  A tribe in Sudan was shown to not become deaf.  Think of some reasons that this would occur.

8.        How do the neurons respond to light?

9.         Is it possible for the eye to function but the brain to not process the image?  Describe how this can happen.

 

1)       Smell and taste are intimately linked.  When you have a cold and your nose is stuffed up, food often tastes very bland.  This is because

a)       The photoreceptors of the toung can only distinguish 3 tastes

b)       The chemical receptors of the taste buds can only distinguish four tastes

c)       The chemical receptors of the taste buds can distinguish hundreds of different tastes

d)       Smell is a large portion of your taste sensation and when your nose is not working you only sense the food with your tongue

2)       What type of receptors detect heat?

a) chemoreceptors       b) mechanoreceptors           c) Photoreceptors                                d) thermoreceptors

3)       Which of the following correctly indicates the difference between pain reception and pain sensation?

a)       There really is no difference, reception and sensation occur at the same time in nociceptors.

b)       Pain reception occurs at a nerve whose function is to form an action potential when pain occurs, Pain sensation occurs in the brain.

c)       Pain reception is in the autonomic portion of the CNS and pain sensation is in the sympathetic portion of the CNS

d)       Pain reception occurs in the CNS and pain sensation occurs in the PNS

Answers: 1) b,d 2) d 3) b

http://isnet.is.wfu.edu/bgsm/nba/faculty/miller/miller.html

a site on this researches work.  Is looking pretty cool.

 

A really cool interactive site on the brain and intelligence

http://www.brain.com/

 

exorcises for the eyes?  Who knows, but it probably does not hurt.

http://www.fitfun.com/eyes.html

 

Neuronal eye simulator look at how eye movements are controlled, requires shock wave http://cim.ucdavis.edu/Eyes/eyesim.htm