Name: 
 

Gilead Quiz 5 Immunology and HIV



True/False
Indicate whether the statement is true or false.
 

 1. 

The maturation of T lymphocytes occurs in the bone marrow.
 

 2. 

Cytotoxic T cells are the only T cells that directly attack and kill pathogens.
 

 3. 

Allergic reactons are caused by inappropriate responses by the immune system to nonpathogenic antigens.
 

 4. 

The major role of antigen-presenting cells in immunity is to engulf antigens and then present fragments of these antigens, like signal flags, on their own surfaces where they can be recognized by T cells.
 

 5. 

A mild fever may be beneficial in fighting an infection.
 

 6. 

Reverse transcriptase inhibitors work by stopping the manufactured viral proteins from assembling into new viruses.
 

 7. 

Helper T cells are responsible for the activation of killer T cells and B cells.
 

Multiple Choice
Identify the choice that best completes the statement or answers the question.
 

 8. 

Which of the following is NOT one of the nonspecific defenses?
a.
antibody agglutination
c.
stomach acidity
b.
complement fixation
d.
antimicrobial enzymes in sweat and tears
 

 9. 

When lymphocytes clone they produce:
a.
alpha and beta cells
c.
memory cells and active cells
b.
antigen presenting cells and killer cells
d.
T cells and antibodies
 

 10. 

Which of the following is NOT a characteristic of inflammation?
a.
swelling
c.
increased capillary permeability
b.
redness
d.
all of the above are characteristics
 

 11. 

Vaccinations are example of:
a.
naturally aquired immunity
c.
artificially aquired immunity
b.
passive immunity
d.
nonspecific immunity
 

 12. 

These cells are the main mediators of allergic responses.
a.
neutrophils
d.
T cells
b.
macrophages
e.
eosinophils
c.
B cells
 

 13. 

Which of the following is NOT a lymphatic organ?
a.
tonsil
d.
thymus
b.
spleen
e.
all of the above are lymphatic organs
c.
lymph node
 

 14. 

The lymphatic organ that screens blood for pathogens is:
a.
spleen
c.
tonsils
b.
lymph nodes
d.
appendix
 

 15. 

Vaccinations depend on the production of                       in order to provide immunity.
a.
killer T cells
c.
antibodies
b.
memory cells
d.
interferon
 

 16. 

The immune system cell that requires an introduction to it's antigen by an antigen presenting cell is the:
a.
B cell
c.
neutrophil
b.
macrophage
d.
T cell
 

 17. 

Select the correct statement about lymphocytes.
a.
B cells produce plasma cells, which secrete antibodies into the blood
c.
T cells are the precursors of B cells
b.
T cells are the only form of lymphocyte found in lymph nodes
d.
the two main types are T cells and macrophages
 

 18. 

Which of the following is NOT generally considered a defense mechanism against disease?
a.
fever
c.
ATP synthesis
b.
intact skin
d.
phagocytosis
 

 19. 

The virally infected cell:
a.
produces complement to help other cells guard against infection
c.
usually dies before the virus has a chance to replicate
b.
produces histamines that initiate complement
d.
produces interferon to help other cells guard against infection
 

 20. 

Which leukocyte is most numerous in a normal person’s system?
a.
basophil
d.
neutrophil
b.
monocyte
e.
eosinophil
c.
lymphocyte
 

 21. 

The secondary response to an infection is:
a.
faster than the primary response
d.
less than the primary response
b.
slower than the primary response
e.
both a and c
c.
greater than the primary response
 

 22. 

Which of the following is a first line defense against viral infection?
a.
phagocytosis of virus by macrophages
c.
cloning of T cells in response to exposure to virus
b.
recognition of viral antigens by B cells
d.
mucus that traps virus and moves it out of respiratory tract
 

 23. 

Which of the following describes a virus?
a.
a unicellular organsim with cell walls
c.
infectious protein
b.
a multicellular organism that parasitizes humans
d.
infectious agents containing nucleic acids
 

 24. 

Which cell is targeted by the HIV virus?
a.
macrophage
c.
helper T cell
b.
B cell
d.
supressor T cell
 

 25. 

The cells that engulf bacteria, viruses and other pathogens are known as:
a.
T lymphocytes
c.
B lymphocytes
b.
macrophages
d.
eosinophils
 

 26. 

Which of the following Gilead formulations contains a three drug “cocktail” to combat HIV?
a.
Emtriva
c.
Atripla
b.
Truvada
d.
Viread
 

 27. 

In the viral lifecycle of HIV, the virus enters the host cell by:
a.
diffusion through the phospholipid bilayer
c.
exocytosis
b.
injection of its nucleic acids into the cytoplasm
d.
endocytosis
 

Matching
 
 
Match the Phase of HIV infection with the following characteristics
a.
phase I
c.
phase III
b.
phase II
 

 28. 

patient experiences full blown AIDS with many opportunistic infections and cancers
 

 29. 

patient may be symptomless, but T cell count is declining, this is the phase that HAART can extend
 

 30. 

initial infection occurs, patient may experience flu-like symptoms
 



 
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