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Gilead Quiz 8 Pathophysiology Topics

True/False
Indicate whether the statement is true or false.
 

 1. 

One consequence of inadequate albumin production by the liver is edema.
 

 2. 

Reverse trancriptase inhibitors (RTIs) work by preventing the HIV genetic material from being copied into DNA in the infected cell.
 

 3. 

A mild fever may be beneficial in fighting an infection.
 

 4. 

Arteries carry oxygenated blood to veins.
 

 5. 

Most people don’t have developing atherosclerosis in their arteries.
 

 6. 

Allergic reactons are caused by inappropriate responses by the immune system to pathogenic antigens.
 

 7. 

Helper T cells are responsible for the activation of killer T cells and B cells.
 

 8. 

Interferons protect cells from viral invasion.
 

 9. 

Blood levels of liver enzymes are useful in detecting liver damage by hepatitis.
 

 10. 

Carbon dioxide retention leads to alkalosis.
 

 11. 

Sympathetic stimulation of the bronchioles causes them to dilate.
 

Multiple Choice
Identify the choice that best completes the statement or answers the question.
 

 12. 

Which of the following is NOT a function of proteins in the body?
a.
cell membrane transporters
d.
chemical messengers
b.
primary fuel source for cells
e.
oxygen transport
c.
enzymes
 

 13. 

The primary function of hemoglobin is to:
a.
store iron
c.
transport glucose
b.
give RBCs their color
d.
carry oxygen to peripheral tissues
 

 14. 

Which of the following blood components has an immune function?
a.
albumin
c.
antibodies
b.
hemoglobin
d.
lipoproteins
 

 15. 

A typical human will have:
a.
20-40 Liters of blood
c.
1-2 Liters of blood
b.
10-20 Liters of blood
d.
4-6 Liters of blood
 

 16. 

Chest pain that is generally associated with lack of adequate blood flow to the heart is termed:
a.
angina
c.
athersosclerosis
b.
arrythmia
d.
angioplasty
 

 17. 

Which of the following describes the flow of information during protein synthesis?
a.
DNA to RNA to DNA
c.
RNA to DNA to protein
b.
DNA to RNA to protein
d.
protein to DNA to RNA
 

 18. 

The site of translation in the cell is:
a.
mitochondrion
c.
ribosome
b.
endoplasmic reticulum
d.
tRNA
 

 19. 

If the left AV valve fails:
a.
cardiac output is decreased
c.
blood pressure in the lungs falls
b.
cardiac output is increased
d.
the blood flow to the aorta increases
 

 20. 

Which cell is targeted by the HIV virus?
a.
macrophage
c.
helper T cell
b.
B cell
d.
supressor T cell
 

 21. 

Which of the following Gilead formulations contains a three drug “cocktail” to combat HIV?
a.
Emtriva
c.
Atripla
b.
Truvada
d.
Viread
 

 22. 

The period of time when the ventricles are relaxing is known as:
a.
systole
b.
diastole
 

 23. 

Which of the following is a characteristic of arteries and arterioles.
a.
they have one way valves
c.
they have a pulsatile pressure
b.
they use breathing to help move blood
d.
their walls consist of a single layer of endothelium
 

 24. 

Which of the following is true of pulmonary arterial hypertension (PAH)?
a.
it is linked to pulmonary blood pressures as high as 15mmHg
c.
it may be treated by drugs that regulate pulmonary artery vasoconstriction
b.
it may cause anemia
d.
it may have symptoms of coughing up of blood
 

 25. 

Which of the following is NOT true of wet age related macular degeneration?
a.
the blood vessels of the eye grow and get leaky
d.
is a leading cause of blindness in the elderly
b.
the arteries of the eye are hypertensive
e.
blood in the vitreous humor prevents light from striking the retina
c.
can be treated by Macugen
 

 26. 

When lymphocytes clone they produce:
a.
alpha and beta cells
c.
memory cells and active cells
b.
antigen presenting cells and killer cells
d.
T cells and antibodies
 

 27. 

Which of the following is NOT a characteristic of inflammation?
a.
swelling
c.
increased capillary permeability
b.
redness
d.
all of the above are characteristics
 

 28. 

Vaccinations are example of:
a.
naturally aquired immunity
c.
artificially aquired immunity
b.
passive immunity
d.
nonspecific immunity
 

 29. 

The cells that engulf bacteria, viruses and other pathogens are known as:
a.
T lymphocytes
c.
B lymphocytes
b.
macrophages
d.
eosinophils
 

 30. 

In the viral lifecycle of HIV, the virus enters the host cell by:
a.
diffusion through the phospholipid bilayer
c.
exocytosis
b.
injection of its nucleic acids into the cytoplasm
d.
endocytosis
 

 31. 

Bacteria residing in the large intestine release ________, which is absorbed by the human host and used for the process of blood clotting.
a.
vitamin D
c.
vitamin K
b.
vitamin E
d.
niacin
 

 32. 

A condition caused by high levels of bilirubin in the blood, causing the skin to take on a yellowish color
a.
jaundice
c.
pain in R upper quadrant
b.
vomiting
d.
ascites
 

 33. 

Which of the following parts of the nephron is most responsible for the ability of the kidneys to concentrate urine?
a.
glomerular apparatus
c.
loop of Henle
b.
proximal convoluted tubules
d.
collecting duct
 

 34. 

What is the normal glomerular filtration rate for adults?
a.
120ml/min
c.
45ml/min
b.
100ml/min
d.
150ml/min
 

 35. 

The majority of filtrate is reabsorbed at:
a.
distal tubule
c.
glomerulus
b.
proximal tubule
d.
loop of Henle
 

 36. 

In the venous blood with normal oxygen levels, hemoglobin is:
a.
100% saturated
c.
75% saturated
b.
95% saturated
d.
25% saturated
 

 37. 

Which of the following is NOT a component of the respiratory membrane?
a.
alveolar epithelium
c.
capillary epithelium
b.
podocytes
d.
surfactant
 

 38. 

The purpose of a sputum sample:
a.
is to use the color to diagnose a lung infection
c.
is to help the patient expel excessive mucus
b.
is to test the sample for antibodies to the infectious agent
d.
is to find the causative agent  of a lung infection
 

 39. 

The structures that form a sealed space around the lungs are called:
a.
epipleurium
c.
serous epithelium
b.
pleural membranes
d.
pulmonary viscose
 

 40. 

The antiviral medication Tamiflu, fights influenza virus by:
a.
inhibiting the reverse transcriptase enzyme
c.
preventing the assembling and budding out of new virus
b.
activating the immune system
d.
preventing the integration of the viral RNA into the host DNA
 

 41. 

What Gilead drug is used to treat pulmonary aspergillosis?
a.
Ambisome
c.
Relenza
b.
Tamiflu
d.
Viread
 

Matching
 
 
Match the following characteristics to the organelles they represent.
a.
producer of cellular ATP
d.
enzymatic digesters
b.
maker of cellular proteins
e.
holder of the genetic material
c.
machinery for ciliary motion
 

 42. 

microtubules
 

 43. 

lysosomes
 

 44. 

nucleus
 

 45. 

mitochondria
 

 46. 

rough endoplasmic reticulum
 
 
Match the Phase of HIV infection with the follwoing characteristics
a.
phase I
c.
phase III
b.
phase II
 

 47. 

patient experiences full blown AIDS with many opportunistic infections and cancers
 

 48. 

patient may be symptomless, but T cell count is declining, this is the phase that HAART can extend
 

 49. 

initial infection occurs, patient may experience flu-like symptoms
 
 
Match the following types of  hepatitis to their charactersitics.
a.
Hepatitis A
c.
Hepatitis C
b.
Hepatitis B
d.
drug induced hepatotoxicity
 

 50. 

Caused by ingestion of toxic drugs or alcohol
 

 51. 

Causes chronic liver disease, but can be vaccinated against
 

 52. 

Fecal oral transmission, seen in day care centers
 

 53. 

Causes chronic liver disease, and can not be vaccinated against
 



 
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